Hexapeptide-11 (Peptamide™ 6)

What is Peptamide™ 6?

Peptamide™ 6, also known as Hexapeptide-11, is a synthetic hexapeptide with the sequence Phe-Val-Ala-Pro-Phe-Pro (FVAPFP). This peptide is derived from stress-related proteins (e.g., hsp70) and transmembrane proteins, which are integral to cellular function and skin health. Its unique composition enhances skin renewal, hydration, and elasticity, making it an advanced ingredient for anti-aging and skin-tightening formulations.

Key Activities

Peptamide™ 6 upregulates genes in five functional areas, offering diverse benefits:

1. Transmembrane Proteins:
   These proteins facilitate the movement of cellular materials across membranes, optimizing cellular function and nutrient exchange.

2. Growth Factors:
   Stimulates fibroblasts, key cells responsible for tissue differentiation, skin repair, and the production of keratinocytes.

3. Matrix Proteins:
   Enhances the production of extracellular matrix (ECM) components, including collagen and elastin, to improve skin elasticity, firmness, and turgor.

4. Skin Lipid Development:
   Promotes the formation and integrity of skin lipids, strengthening the lipid bilayer and enhancing barrier function.

5. Cell Shock/Stress Proteins:
   Activates chaperone proteins that protect cells from damage due to environmental stress, preserving cellular health and resilience.

Benefits of Peptamide™ 6

1. Anti-Aging:

   • Stimulates fibroblast activity to rejuvenate and repair the skin.
   • Improves collagen and elastin production for a youthful, plump appearance.

2. Skin Tightening:

   • Strengthens the extracellular matrix for firmer, more elastic skin.

3. Hydration:

   • Enhances skin’s water retention by improving lipid integrity and barrier function.

4. Cellular Protection:

   • Protects cells from stress-related damage by upregulating stress proteins and preventing protein denaturation.

5. Skin Renewal:

   • Encourages cellular turnover and tissue growth for smoother, fresher skin.

Applications

Peptamide™ 6 is ideal for use in:

• Anti-Aging Creams and Serums: Reduces wrinkles and promotes skin renewal.
• Firming and Lifting Products: Improves skin elasticity and tightness.
• Hydrating Formulations: Enhances water retention and skin barrier function.
• Skin Repair Products: Supports cellular recovery and resilience.

Functions

• Anti-Aging
• Skin Tightening
• Hydrating

Why Choose Peptamide™ 6?

Peptamide™ 6 is a scientifically advanced peptide that targets multiple pathways for skin health. Its ability to stimulate growth factors, enhance the extracellular matrix, and improve skin lipids makes it a versatile and effective ingredient in skincare formulations aimed at firming, hydration, and anti-aging.